SOLADOXY®500

1 g contains 500 mg of doxycycline hyclate

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Pharmacological properties

Doxycycline hyclate is a semi-synthetic tetracycline antibiotic with a broad spectrum of bacteriostatic action against gram-positive (Staphylococcus spp., Streptococcus spp., Actinomyces spp., Clostridium spp., Bacillus anthracis, Corinebacterium spp., Erysipelotrix spp., Listeria spp.) and gram-negative (Haemophilus influenzae, Haemophilus parasuis, Pauterella multocida, Bordetella spp., Brucella spp., Bartonella spp., Actinobacillus pleuropneumoniae, Escherichia coli, Salmonella spp., Campylobacter spp.) microorganisms, Spirocheata spp., Chlamidia spp. and Rickettsia spp. Doxycycline inhibits the synthesis of proteins in the microbial cell, disrupting transport aminoacyl-RNA to 30S-subunit of ribosomal membrane.

Indications

• Treatment and prevention of respiratory and gastrointestinal diseases of bacterial etiology in calves, lambs, goats, pigs and poultry, caused by doxycycline-sensitive microorganisms.

Dosage

SOLADOXY® 500 is administered with drinking water for 3-5 days as follows: Calves, lambs, goats – 0.1 g per 10 kg of bw (5 mg of doxycycline/kg bw), individually, twice a day. Pigs and poultry – by group method at daily dose of 100 g per 500-1000 L of water.

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