Pharmacological properties
Oxytocin is a synthetic equivalent of infundibular body polypeptide. The hormone is prepared synthetically to avoid possible contamination with vasopressin (ADH) and other small polypeptides with biologic activity. Oxytocin is capable of enhancing the uterine retraction and mammary gland myoepithelium.
Indications
- Obstetric aid and stimulation of complicated delivery. - Uterine bleeding, retention of the placenta, atony, hypotony of uterus and metritis.
- Mastitis and reflectory agalaxy.
- Uterine bleeding, retention of the placenta, atony, hypotony of uterus and metritis.
Dosage
The drug is administered by a subcutaneous, intramuscular, intravenous injection and if necessary in combination with the epidural injection of novocaine at the following dosage:
Species |
Mode of administration and dosage (IU) |
||
subcutaneous or intramuscular |
intravenous |
epidural |
|
Horses and cows |
30 – 60 |
20 – 40 |
15–30 |
Swine, weighting up to 200 kg |
30 |
20 |
10–15 |
Goats and sheep |
10 – 15 |
8 – 10 |
- |
Dogs |
5 – 10 |
2 – 7 |
- |
Cats |
3 |
3 |
2 |