The combination of clindamycin and spectinomycin has a synergistic effect on gram-positive and gram-negative bacteria, including Staphylococcus spp., Streptococcus spp., Escherichia coli, Salmonella spp., Pasteurella multocida, Haemophilus spp., Proteus spp., Shigella spp., Klebsiella spp., Bordetella spp. and Mycoplasma spp. After parenteral administration, the maximum concentration of the drug is detected in 45 minutes, the therapeutic concentration – within a day. Clindamycin and spectinomycin are mainly excreted in the urine and feces.
The solution for injection is used to treat calves, piglets, sheep, lambs, goatlings, cats and dogs for bacterial infections of respiratory and gastrointestinal tract, genitourinary system, skin and soft tissues caused by microorganisms sensitive to clindamycin and spectinomycin.
1 ml solution for injection contains 50 mg of clindamycin phosphate and 100 mg of spectinomycin hydrochloride.
The antibiotic is administered intramuscularly once a day at a dose of 1 ml per 10 kg bw (5 mg of clindamycin/kg bw and 10 mg of spectinomycin/kg bw) for 3-5 days.