Pulmosol®

Specification

Pulmosol® is an antibacterial drug.
Kitasamycin is a macrolide antibiotic, has a bacteriostatic effect
on gram-positive bacteria – Staphylococcus spp., Streptococcus spp.
(including penicillinase-producing bacteria), Clostridium spp., Bacillus
anthracis, Listeria monocytogenes and some gram-negative bacteria
– Hemophilus spp., Brucella spp., and Mycoplasma spp., Chlamydia
spp., Rickettsia spp., etc. Kitasamycin reversibly binds to the peptidyl
transferase center of the 50S ribosomal subunit and induces the
cleavage of peptidyl-tRNA complex. As a result, it inhibits the peptide
bond formation.
Colistin sulfate is a mixture of sulfate polypeptides produced by
Bacillus polymyxia strains. Colistin has a bactericidal effect on most
aerobic gram-negative bacteria. It is active against Enterobacter
spp., Escherichia coli, Klebsiella spp., Salmonella spp., Pasteurella spp.,
Bordetella spp., Proteus spp. and others. Colistin disrupts cytoplasmic
membrane permeability.
Ascorbic acid has an anti-stress effect and increases the resistance
of the body.
Glycine is an amino acid neurotransmitter, part of many proteins,
forms porphyrins and purine bases in cells.
After oral administration, the components of the drug are quickly
absorbed in the gastrointestinal tract and distributed to most organs
and tissues. There, they reach antibacterial concentration, which
persists for 20-24 hours.
The drug is mainly excreted in the urine and bile.