Amprolium hydrochloride has broad-spectrum anticoccidial activity.
The agent is effective against E. tenella, E. acervulina, E. necatrix,
E. maxima, E. mivati, E. brunetty and other Coccidia affecting poultry.
The anticoccidial activity of Amprolium 30% can be explained by
its similar chemical structure with thiamine (vitamin B1
inhibits carbohydrate metabolism in parasites, which causes their
paralysis and death. The cell membrane of the intestinal mucosa of
poultry and mammals is hardly permeable to Amprolium 30%, it
makes the drug practically non-toxic in the therapeutic doses.
97% of Amprolium 30% are excreted in the feces.
The drug is used for treatment and prevention of coccidiosis in broiler chickens, replacement chickens and breeding flocks.
100 g contains 30 g of amprolium hydrochloride.
Amprolium 30% water-soluble powder is administered to poultry via drinking water or feed at the following doses:
• broilers (over the age of 3-5 days, during rearing): at a daily dose of 200 g of the drug per 500 L of water or 400 g of the drug per 1 t of feed (remove from the ration 5 days before slaughter);
• replacement chickens (over the age of 3-5 days until the age of 16 weeks): at a daily dose of 200 g of the drug per 500 L of water or 400 g of the drug per 1 t of feed, which is equivalent to 120 mg of amprolium per 1 L of water or 1 kg of feed;
• broilers and replacement chickens: at a daily dose of 400 g of the drug per 500 L of water or 800 g of the drug per 1 t of feed, which is equivalent to 240 mg of amprolium per 1 L of water or 1 kg of feed, for 5-7 days.