Enroflon® 10%
Oral solution
Specification
Enrofloxacin is a fluoroquinolone antibiotic, has broad-spectrum
antibacterial activity. The antibiotic inhibits bacterial DNA
replication. The resistance of bacteria to Enroflon® 10% develops
relatively slow, due to the inhibition of bacterial DNA replication.
Enrofloxacin is effective against gram-positive and gram-negative
bacteria, including E. coli, Salmonella spp., Pasteurella haemolytica,
Pasteurella multocida, Staphylococcus aureus, Staphylococcus
hyicus., Streptococcus spp., Klebsiella spp., Pseudomonas aeruginosa,
Bordetella bronchiseptica., Campylobacter spp., Corynebacterium
pyogenes, Proteus spp., Mycoplasma spp., Brucella canis, Actinobacillus spp., Listeria monocytogenes, Haemophilus spp., Clostridium
perfringens, etc. Enroflon® 10% oral solution is well absorbed in
the gastrointestinal tract and quickly distributed to all organs and
tissues. The maximum concentration in the blood is reached in 1-2
hours and persists for 6 hours. The therapeutic concentration persists
for 24 hours. Enrofloxacin is partially metabolized to ciprofloxacin.
Enrofloxacin and ciprofloxacin are excreted primarily intact in the
urine and bile.
Indications
Enroflon® 10% solution for injection is used to treat calves, lambs,
pigs and poultry for colibacillosis, salmonellosis, mycoplasmosis,
bronchopneumonia, enteritis and other diseases caused by
fluoroquinolone-sensitive bacteria; to treat pigs for atrophic rhinitis,
enzootic pneumonia and mastitis-metritis-agalactia syndrome.
Composition
1 ml oral solution contains 100 mg of enrofloxacin.
Dosage
The drug is administered via drinking water once a day for 3-5 days at the following doses:
• calves, lambs and piglets: 2.5-5.0 mg of enrofloxacin per 1 kg bw;
• broilers and turkeys: 0.5-1 L per 1 t of water.