Specification
Oxytetracycline hydrochloride 1000 is a broad-spectrum antibacterial drug, active against gram-positive and gram-negative bacteria, Spirochaetas spp., Leptospira spp., Rickettsia spp., Chlamydia spp., Mycoplasma spp. The antibiotic has no effect on Proteus spp. and Pseudomonas aeruginosa. The drug inhibits protein synthesis. After oral administration, oxytetracycline hydrochloride is well absorbed in the gastrointestinal tract and distributed to all organs and tissues. The maximum concentration is reached in 2-3 hours after administration and persists for 8-12 hours. Oxytetracycline hydrochloride 1000 is excreted partially in the urine and mainly in the feces.
Indications
The drug is used to treat livestock and poultry for colibacillosis, salmonellosis, pasteurellosis, dysentery, pullorosis, eimeriosis, infectious respiratory diseases, respiratory mycoplasmosis, mastitis, endometritis, vaginitis, infectious kidney diseases and urinary diseases; for treatment of mucous membranes of skin wounds (as a 0.5-3% solution or ointment).
Composition
Oxytetracycline hydrochloride 1000 contains water-soluble antibiotic salt produced by Streptomyces rimosus, oxytetracycline hydrochloride.
Dosage
The drug is administered by oral route during or after feeding, twice a day for 5-7 days at the following doses: horses – 5-8 mg/kg bw, cattle – 10-20 mg/kg bw, sheep and goats – 10-30 mg/kg bw, pigs – 15-30 mg/kg bw, poultry – 20-40 mg/kg bw.