Solamox®
Suspension for injection intramuscular and subcutaneous administration
Specification
Solamox® belongs to the penicillin class of antibiotics.
Amoxicillin trihydrate is a broad-spectrum antibiotic, has a
bactericidal effect on gram-positive and gram-negative bacteria,
including Clostridium spp., Fusobacterium spp., Bacillus antracis,
Streptococcus spp., Actynomyces spp., Corynebacterium spp., Salmonella
spp., Heamophilus spp., Pausterella spp., Actinobacillus spp., Leptospira
spp. and other amoxicillin-sensitive pathogens. The antibiotic is not
active against penicillin-producing strains, Klebsiella spp., Enterobacter
spp. and Pseudomonas spp.
Amoxicillin inhibits bacterial cell wall synthesis, activity of
transpeptidase and carboxypeptidases, disrupts osmosis. It causes
death of bacteria at the growth stage. Amoxicillin is well absorbed
from the injection site and quickly distributed to organs and tissues
after parenteral administration. The maximum concentration
is reached in 1-2 hours after administration and persists at the
therapeutic level for 48 hours.
Amoxicillin is metabolized and excreted mainly in the urine and to a
lesser extent in the milk.
Indications
Solamox® is used to treat cattle, sheep, pigs and dogs for diseases of gastrointestinal, respiratory, urinary tract, joints, soft tissues, skin, mastitis, postoperative, wounds and other primary and secondary infections caused by amoxicillin-sensitive bacteria.
Composition
1 ml contains 150 mg of amoxicillin trihydrate and excipients – up to 1 ml.
Dosage
Solamox® is administered once by intramuscular or subcutaneous route at a dose of 1 ml per 10 kg bw (15 mg of amoxicillin per 1 kg/bw). If necessary, the drug can be administered again in 48 hours. The maximum allowable volumes to administer to one injection site are 20 ml for cattle, 5 ml for sheep, 10 ml for pigs and 2.5 ml for dogs. If the recommended doses exceed the quantities specified, the drug must be administered to several injection sites.