Specification
Solamox® is an antibacterial drug.
Amoxicillin is a semisynthetic antibiotic, belongs to the penicillin
class. It has a bactericidal effect on gram-positive and gramnegative bacteria, including Staphylococcus spp. Streptococcus suis,
Streptococcus faecalis, Streptococcus pneumoniae, Arcanobacterium
pyogenes, Corynebacterium bovis, Erysipelothrix rhusiopathiae, Listeria
monocytogenes, Bacillus anthracis, Clostridium perfringens, Hemophilus
spp., Pasteurella spp., Escherichia coli, Salmonella spp., Proteus mirabilis,
Morexella bovis, Fusobacterium necrophorus, Brachyspira hyodysenteriae.
Amocicillin is not active against β-lactamase-producing bacteria.
Amoxicillin disrupts cell wall synthesis, inhibits the formation of
transpeptide bonds, which are necessary for peptidoglycan crosslinking.
After oral administration, amoxicillin is quickly absorbed in the
gastrointestinal tract and distributed to most organs and tissues.
The antibiotic reaches the maximum concentration in 1-2 hours after
administration. The constant administration of the drug via water or
feed keeps the therapeutic concentration within the whole treatment
course.
Indications
Solamox® is used for treatment and prevention of respiratory and gastrointestinal bacterial infections in calves, pigs and poultry caused by amoxicillin-sensitive bacteria.
Composition
1 g contains active substance: 700 mg of amoxicillin trihydrate: excipients: 270 mg of sodium carbonate, 20 mg of glycine, 10 mg of trilon B.
Dosage
Solamox® is administered via feed or drinking water at the following daily doses:
• calves: 150 mg of the drug per 10 kg bw (10 mg of amoxicillin per 1 kg bw), twice a day with a 12-hour interval for 5 days. The drug can also be administered via milk or milk replacer;
• pigs: 150-300 mg of the drug per 10 kg bw (10-20 mg of amoxicillin per 1 kg bw) for 5 days;
• poultry: 20 mg of the drug per 1 kg bw (14 mg of amoxicillin per 1 kg bw) for 5 days.