Floricol®

Oral solution

Антибактериальные: свинья Антибактериальные: индюк Антибактериальные: курица
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Specification

Floricol® is an antibacterial drug. Florfenicol is a synthetic antibiotic, thiamphenicol derivative. The hydroxyl group is substituted by a fluorine atom. Florfenicol is a broad-spectrum bacteriostatic antibiotic. The antibiotic binds to the 50S ribosomal subunit, inhibits peptidyl transferase activity, as a result it leads to the inhibition of protein synthesis. Florfenicol is active against gram-positive and gram-negative bacteria: Staphylococcus spp., Streptococcus spp., Escherichia coli, Salmonella spp., Actinobacillus pleuropneumoniae, Pasteurella multocida, Pasteurella haemolitica, Haemophilus spp., Fusobacterium necrophorum, Proteus spp., Enterobacter spp., Shigella spp., Klebsiella spp., Bordetella spp., and Mycoplasma spp. After oral administration, florfenicol is rapidly absorbed and distributed to all organs and tissues. The antibiotic reaches the maximum concentration in 40-60 minutes, the therapeutic concentration persists for 24 hours. Bioavailability of florfenicol in pigs is 88%, poultry – 55%. Florfenicol and its metabolites (florfenicol amine) are excreted primarily in the bile and feces.

Indications

Floricol® is used for treatment and prevention of colibacillosis, salmonellosis, pasteurellosis, staphylococcosis and other bacterial diseases in poultry caused by florfenicol-sensitive bacteria, and atrophic rhinitis, pleuropneumonia and secondary bacterial infections in pigs.

Composition

1 ml contains active substances: 100 mg of enrofloxacin and 2 000 000 IU of colistin sulfate; excipients: 187.5 mg of lactic acid, 150 mg of propionic acid, 90 mg of propylene glycol, 10 mg of ascorbic acid and distilled water-up to 1 ml.

Dosage

Floricol® is administered to pigs and poultry via drinking water.Floricol® is administered at a daily dose of 20 mg of florfenicol per 1 kg bw for 3-5 days.

•  chickens under the age of 4 weeks – 100 ml of the drug per 100 L of water

•  poultry over the age of 4 weeks – 200 ml of the drug per 100 L of water.

Floricol® is administered to pigs at a dose of 5 mg of florfenicol per 1 kg bw (5 ml of the drug per 100 kg bw) for 7 days.