Gentamicin belongs to the aminoglycoside class of antibiotics. It
has a broad-spectrum antibacterial effect on most gram-positive and
some gram-negative bacteria, including Proteus spp., Escherichia spp.,
Salmonella spp. and Staphylococcus spp. The antibiotic has no effect on
anaerobic bacteria, viruses and protozoa.
The antibiotic reaches the maximum concentration in an hour after
administration. After a single injection the therapeutic concentration
persists within 8-12 hours after administration.
GENTAMICIN is excreted intact primarily in the urine.
The drug is used to treat animals for respiratory, gastrointestinal diseases, sepsis, peritonitis, meningitis, pyelonephritis and other diseases caused by gentamicin-sensitive microorganisms.
1 mlsolution for injection contains 40 mg of gentamicin sulfate.
The drug is administered intramuscularly twice a day with a 10-12 hour interval at the following doses:
• cattle – 3 mg/kg bw for 3-5 days;
• horses – 2.5 mg/kg bw for 3-5 days;
• pigs – 4 mg/kg bw for 1-3 days;
• cats and dogs – 2.5 mg/kg bw for 3-7 days.