Lincoprem 150
Oral granules
Specification
Lincoprem 150 is an antibacterial drug. Lincomycin hydrochloride is a lincosamide antibiotic. The antibiotic has a bacteriostatic effect on Staphylococcus spp., Streptococcus spp. (including penicillinaseproducing strains) Corynebacterium spp., Brachyspira spp., Lawsonia intracellularis, Clostridium spp., Bacteroides spp. and Mycoplasma spp. Due to the binding with the 50S subunit, lincomycin inhibits protein synthesis at the ribosomal level. After oral administration, lincomycin is absorbed in the gastrointestinal tract and distributed to most organs and tissues. The maximum concentration in the blood is reached in 3-6 hours after drug administration. Lincomycin is excreted intact mainly in the urine and feces.
Indications
Lincoprem 150 is used for treatment and prevention of mycoplasma and bacterial diseases (dysentery, ileitis, clostridiosis, streptococcosis, etc.) in pigs and poultry caused by lincomycin-sensitive bacteria.
Composition
1 g contains 150 mg of lincomycin hydrochloride and excipients.
Dosage
Lincoprem 150 is administered via feed at the following daily doses:
• pigs: 300-750 g/t of feed, for 3 weeks;
• poultry: for treatment and prevention of necrotic enteritidis –
250-500 g/t of feed, for 7-10 days.
For treatment and prevention of diseases caused by anaerobic
bacteria in poultry (chickens, turkey poults), the drug is administered
at a dose of 750 g/t of feed for 10-20 days.